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Found 38 from Kobe Pharmaceutical University
TargetBeta-secretase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50157441(5-((2R,3S)-3-((S)-2-((S)-2-((S)-2-amino-3-(2H-tetr...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM28476((2S)-2-({12-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452615(CHEMBL4217377)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452613(CHEMBL4207732)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452613(CHEMBL4207732)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM28476((2S)-2-({12-[(4-fluorophenoxycarbonyl)amino]-8-oxa...)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452615(CHEMBL4217377)
Affinity DataIC50:  69nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452616(CHEMBL4218681)
Affinity DataIC50:  297nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452616(CHEMBL4218681)
Affinity DataIC50:  403nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452614(CHEMBL4214104)
Affinity DataIC50:  502nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50452614(CHEMBL4214104)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198194(CHEMBL3978947)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50190131(Oblongifolin C)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50448068(Guttiferone K)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198198(CHEMBL3889506)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50385113(CHEMBL2036099)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of Wistar/ST rat lung NAAA assessed as conversion of [14C]PEA to [14C]palmitic acid after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198200(CHEMBL3976184)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198195(CHEMBL3917534)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198197(CHEMBL3907489)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198196(CHEMBL3898463)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198193(CHEMBL3926514)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198199(CHEMBL3935433)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020659(CHEMBL3290498)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50385114(CHEMBL2035895)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of Wistar/ST rat lung NAAA assessed as conversion of [14C]PEA to [14C]palmitic acid after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020663(CHEMBL3290502)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020676(CHEBI:41846 | CHEMBL566812)
Affinity DataIC50:  2.87E+4nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020676(CHEBI:41846 | CHEMBL566812)
Affinity DataIC50:  3.08E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020661(CHEMBL3290500)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269441(CHEMBL465592 | Isorauhimbinic acid)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020664(CHEMBL3290503)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020662(CHEMBL3290501)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50020660(CHEMBL3290499)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Rattus norvegicus)
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090910(3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat recombinant DNA polymerase beta expressed in Escherichia coli JMpbeta5 cells assessed as incorporation of [3H]dTTP into poly(dA)/ol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50017712((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase lambda(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50090910(3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed